{Mohanasankar Sivaprakasam Keerthi Ram JM Poorneshwaran Sakthivel Selvaraj Kamalakkannan Ravi}

Abstract

In this work, in order to improve the computer aided diagnosis systems’ performance on histopathological image analysis, we have proposed an approach with image pre-processing followed by a deep learning method to classify the breast cancer histology images into four classes; (i) normal tissue, (ii) benign lesion, (iii) in-situ carcinoma, and (iv) invasive carcinoma. The images are preprocessed for intensity and stain normalization using histogram equalization method. The Fine-tuning ConvNet transfer learning method is used with ResNet152 to train and classify the images. This proposed approach yields an average fivefold cross validation accuracy of 83%, a substantial improvement over the state-of-the-art.